Table 2.

[¹⁸F]FCWAY V/f₁ Values in Temporal Lobe Epilepsy (TLE) Patients with and without Major Depressive Disorder (MDD) and Healthy Controls.

Region	TLE with MDD		TLE w/o MDD		Group	Lateralitya	G-L Interaction
	Mean	SD	Mean	SD	F, p	F, p	F, p
Anterior Cingulate	46.29	10.18	56.83	12.65	6.86, .013	-	-
Posterior Cingulate Raphe Nucleus	43.36 21.83	9.47 5.45	52.52 27.65	15.10 7.45	4.57, .040 7.13, .011	- -	- -
Anterior Insula					6.85, .013	1.05, .314	0.24, .626
Left	46.97	7.46	54.82	13.05
Right	46.87	11.09	56.70	12.68
Hippocampus					14.00, .001	0.00, .984	6.44, .016
Left	79.99	16.52	91.30	31.93
Right	69.21	16.16	98.35	18.68
Amygdala					3.16, .084	0.86, .361	5.00, .032
Left	60.82	24.26	65.60	21.00
Right	55.78	20.01	71.54	17.97
Cerebellum					0.05, .832	0.19, .663	0.34, .561
Left	23.42	20.37	18.83	7.95
Right	22.13	17.89	18.19	8.60
Frontal Lobe					2.35, .134	42.02, .000	0.08, .781
Left	58.54	24.68	64.44	16.42
Right Fusiform Gyrus	62.58	15.47	72.75	20.55	3.09, .088	0.44, .512	0.69, .413
Left	83.57	20.02	93.78	37.66
Right	82.81	19.95	100.78	25.68
Occipital Lobe					2.85, .101	0.64, .802	0.02, .903
Left	46.50	13.28	54.01	13.87
Right	46.64	15.47	54.41	13.61
Parietal Cortex					3.97, .054	1.65, .21	0.06, .81
Left	53.72	14.54	66.20	20.14
Right	55.66	17.10	68.16	19.75
Parahippocampal Gyrus					3.98, .054	0.82, .371	4.31, .045
Left  Right	89.98 86.23	16.66 20.61	98.45 104.73	31.49 21.52
Temporal Lobe: Inferior					3.25, .080	1.56, .220	2.42, .129
Left	80.93	19.87	90.58	32.77
Right	79.92	16.59	99.55	28.97
Medial					4.16, .049	12.75, .001	0.65, .424
Left	69.88	15.44	79.97	25.51
Right	78.59	13.86	94.80	26.03
Superior					6.63, .014	15.46, .000	3.70, .063
Left	64.11	18.98	72.88	20.37
Right	69.44	17.57	92.62	24.63

^aLaterality refers to right versus left anatomical side and is not related to epileptic focus