Table 2.
Donor | Recipient | Time post-Tx (days) | Treatment | OAD Lesions (% of Allografts) | ||
---|---|---|---|---|---|---|
Epithelial Damage | Cellular Infiltration | Lumen Occlusion | ||||
H13a | H13b | 30 | - | 25 | 25 | 0 |
H13a | H13b | 60 | - | 100 | 100 | 0 |
H13a | H13b | 90 | - | 100 | 100 | 100 |
H13b | H13b | 30 | - | 0 | 0 | 0 |
H13b | H13b | 60 | - | 0 | 0 | 0 |
H13b | H13b | 90 | - | 0 | 0 | 0 |
Pre-transplant sensitization (subcutaneous injection of peptide) | ||||||
H13a | H13b | 30 | SVL9 | 100 | 100 | 50 |
H13a | H13b | 60 | SVL9 | 100 | 100 | 75 |
H13a | H13b | 90 | SVL9 | 100 | 100 | 100 |
H13a | H13b | 30 | SIL9 | 25 | 25 | 0 |
H13a | H13b | 60 | SIL9 | 100 | 100 | 0 |
H13a | H13b | 90 | SIL9 | 100 | 100 | 100 |
Pre-transplant tolerization (intravenous injection of peptide) | ||||||
H13a | H13b | 90 | SVL9 | 0 | 0 | 0 |
H13a | H13b | 90 | SIL9 | 100 | 100 | 100 |
BALB/c | H13b | 30 | SVL9 | 100 | 100 | 100 |