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. 2005 Dec 19;171(6):1001–1012. doi: 10.1083/jcb.200508072

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Copyright © 2005, The Rockefeller University Press

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Figure 1. — Electron micrographs of HD mouse brains. (A–D) EM48 immunogold labeling of the striatum (A) and cortex (B–D) of R6/2 mice at 12 wk of age. Immunogold-labeled aggregates are present in glial cells (arrows), which show a more condensed nuclear membrane and a smaller sized cytoplasm than do neuronal cells (arrowheads). Bars, 1 μm.