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. 2005 Aug 29;170(5):803–812. doi: 10.1083/jcb.200506131

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Copyright © 2005, The Rockefeller University Press

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Figure 1. — DE-cadherin function during oogenesis. (A) Schematic representation of border cell migration. (B) Wild-type stage 10 egg chamber; border cells (arrow) have reached the oocyte. (C) Border cells (arrow) do not migrate when border or nurse cells are mutant for shg (DE-cadherin). (D) The oocyte (asterisks) is located in the posterior of wild-type egg chambers. (E) Oocyte mislocalization is often observed when follicle or nurse cells are shg mutant. (F and G) Follicle cell sorting; stage 9 egg chambers. Compared with control clones (F), shg mutant clones sort away from wild-type cells to form a smooth interface (G). (H and I) Follicular epithelium integrity; stage 10 egg chambers. shg mutant clones lose epithelial integrity (I, compare cell shape with that of the wild-type clone in H). (B–I) Phalloidin (red) stains F-actin. (F–I) Mutant clones are indicated by an absence of GFP (green). Bars (B and C), 80 μm; (D and E) 50 μm; (F–I) 20 μm.

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