Figure 2.
The effect of cyanide dose on (a) time required for recovery of neuromuscular coordination, and (b) survival. The left y-axis shows the time in min required for the recovery of the righting reflex, while the right y-axis indicates percent survival. The optimum dose for antidote screening was 4.8 mg NaCN/kg body weight, with a resultant 68 min average time required for the recovery of the righting reflex (shown at the arrow). The survival rate at this optimum dose was 94%. The estimated LD50 for NaCN was 6.1 mg/kg (shown at the asterisk). Values reflect means, n= 8/group, except control, i.e., 0 cyanide, n= 20.