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. Author manuscript; available in PMC: 2008 Nov 26.
Published in final edited form as: Chem Biol. 2007 Nov;14(11):1254–1260. doi: 10.1016/j.chembiol.2007.10.007

Figure 1.

Figure 1

Structures of PKC sensors and inhibitors. Compound 1 responds to PKC-catalyzed phosphorylation in a fluorescently sensitive fashion (7). The nonphosphorylatable analogue 2 is converted to the active sensor 1 by photolysis (8). Compound 3 is a selective PKC ß inhibitor (11), whereas compound 4 serves as a selective PKC α inhibitor (12).