Figure 3.
Generation of mice lacking all three MALS isoforms. (A) PCR genotyping of MALS mice. Single asterisk indicates mice that died within hours of birth and double asterisk indicates a line that died in their second postnatal week. (B) Statistics obtained from crossing MALS-1/2 K and MALS-3 H mice. Genotyping 2-wk-old mice showed no TKO mice. However, embryonic mice (E18) showed the predicted ratio of W, H, and K mice.