Table III. Regulation of synaptic genes during development and after denervation.
| Rank | Gene name | Synaptic/ extrasynaptic |
Denervation/ adult |
Embryonic/ adult |
|---|---|---|---|---|
| 1 | AChRɛ | 83.64 | 0.28 | 0.04 |
| 2 | AChRα1 | 56.78 | 25.35 | 3.58 |
| 6 | CD24 | 16.39 | 1.93 | 0.34 |
| 11 | Unc53H3 | 12.86 | 1.35 | 3.17 |
| 12 | MuSK | 11.63 | 4.89 | 7.58 |
| 13 | ERM | 11.40 | 0.93 | 0.47 |
| 14 | nestin | 10.88 | 0.41 | 4.03 |
| 16 | LL5β | 10.40 | 1.95 | 4.04 |
| 18 | NTA | 9.69 | 1.49 | 2.57 |
| 21 | PKARIα | 8.46 | 1.66 | 1.08 |
| 22 | AChRδ | 8.40 | 2.42 | 7.12 |
| 47 | AChE | 5.78 | 0.09 | 1.95 |
| 79 | collagen α3(VI) | 4.82 | 1.08 | 1.58 |
| 122 | ColQ | 4.14 | 1.15 | 1.91 |
| 307 | utrophin | 3.28 | 4.76 | 2.75 |
| 455 | AChRγ | 2.95 | 1.10 | 19.36 |
| 1728 | AChRβ1 | 2.13 | 6.16 | 1.09 |
| 2227 | NCAM | 1.99 | 1.77 | 0.95 |
| 2845 | laminin α5 | 1.88 | 1.35 | 3.40 |
| 4925 | rapsyn | 1.61 | 0.50 | 1.57 |
| 7374 | ErbB3 | 1.44 | 2.83 | 8.69 |
Synaptic enrichment of transcripts previously known to encode synaptic proteins was determined as in Table S1; those with rankings in the top 20% are listed, along with new genes identified in this study. Changes in abundance during development and after denervation were assessed with duplicate microarrays.