Figure 2.

Matrix remodeling and inflammatory gene expression in vivo . C57/B6 mice were fed a chow diet (A), male ApoE null mice were fed a chow diet for 10 wk (B), and ApoE null mice were fed a Western diet for 10 wk (C). Mice were killed and the indicated arteries were removed and embedded in paraffin. Serial sections were stained for FN, FG, ICAM-1, VCAM-1, and Mac-2 and shown at high magnification, with lower magnification views of the entire vessels shown as insets.