Table 2.

Location of heal QTL as determined in the intercross (F2) and the backcross (BC1) progeny

Mouse Genome Database, centimorgans	Primers	F2 LRS*	F2 P value	BC1 LRS†	BC1 P value	QTL
71.5	D1Mit288	6.1	0.0130		ns
105	D2Mit148		nd	4.8	0.0279
55.6	D4Nds2 4.2	4.2	0.0400		ns
77.5	D4Mit127	5.5	0.0190		ns
52.4	D7Mit220		ns	10.2‡	0.0014
21	D8Mit191		ns	6.4	0.0115
33	D8Mit132	5.5	0.0188		ns
37	D8Mit249	7.3	0.0069		ns
49	D8Mit211	10.7	0.0011		ns	heal1‡
56	D8Mit166	7.3	0.0068		nd
34	D12Mit4		ns	7.1	0.0077
52	D12Mit233	6.1	0.0137	9.4	0.0022
52	D12Mit132		nd	10.9	0.0009	heal5‡§
9	D13Mitl35	9.4	0.0022	4.8	0.0290
11	D13Mit115	9.7	0.0019	5.0	0.0261	heal2‡§
13	D13Mitll6	8.7	0.0030	5.1	0.0230
30	D13Mit245	7.5	0.0335		nd
32	D13Nds1	10.2‡	0.0014		ns
44	D13Mit126	7.4	0.0065		ns
44	D13Mit191	10.2‡	0.0014		ns
47	D13Mit29	6.5	0.0101		nd
48	D13Mit107	7.4	0.0064		ns
49	D13Mit144	6.9	0.0088		nd
60	D13Mit129	10.8	0.0010	8.3	0.0040	heal3‡§
62	D13Mit53	10.5	0.0012	7.1	0.0077
71	D13Mit151	8.2	0.0042	4.6	0.0318
54.5	D15Mit171	6.6	0.0104		nd
55.6	D15Mit242	7.1	0.0079		nd
57.8	D15Mit172	7.3	0.0070		nd
56.8	D15Mit244	10.7	0.0011		nd	heal4‡
56.8	D15Mit14	8.5	0.0035		ns

Underlining indicates the LRS values that were used for assigning heal QTL. ns, not significant; nd, not determined. 

^*Threshold LRS for significant linkage = 10.7 and for suggestive linkage = 3.3. 

^†Threshold LRS for significant linkage = 11.8 and for suggestive linkage = 3.7. 

^‡See text for discussion. 

^§Confirmed in second cross.