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. 2005 May 9;169(3):515–526. doi: 10.1083/jcb.200412081

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Copyright © 2005, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure 1. — β1 and β3 integrins differentially affect motile behavior. (A and B) Migration tracks of GEβ1 (A) or GEβ3 cells (B) seeded sparsely on FN-coated coverslips and followed for 16 h. Shown are 20 cells obtained from three independent experiments. (C) Analysis of persistence (ratio of the direct distance from start point to end point divided by the total track distance) and speed of migrating GEβ1 and GEβ3 cells in sparse cultures. (D) Analysis of MTOC polarization in wounding assays with GEβ1 (filled bars) and GEβ3 cells (open bars) at the indicated time points after wounding of confluent monolayers on FN-coated coverslips. Mean ± SD of ∼100 cells analyzed in three independent assays is shown. See supplemental data for the accompanying videos and immunofluorescence images (available at http://www.jcb.org/cgi/content/full/jcb.200412081/DC1).

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