Table 1.
lod score calculations using only the data obtained with affected members of each PHP-Ib kindred
Maximal theoretical lod scores | Kindred
F
|
Kindred P
|
Kindred
D
|
Kindred T
|
Combined 6.89 | θ combined | ||||
---|---|---|---|---|---|---|---|---|---|---|
2.73 | θ | 1.49 | θ | 1.50 | θ | 1.17 | θ | |||
D20S902 | 1.30 | 0.2 | 0.24 | 0.1 | 0.13 | 0.2 | 0.49 | 0 | 2.17 | 0.5 |
D20S120 | 1.80 | 0 | 0.24 | 0.1 | 0.90 | 0 | −0.31 | 0.2 | 2.63 | 0.3 |
D20S100 | 2.16 | 0 | 0.24 | 0.1 | 0.32 | 0.2 | 0.09 | 0.2 | 2.82 | 0.5 |
D20S149 | 2.73 | 0 | 1.49 | 0 | 0.40 | 0 | 0.00 | 0.2 | 4.62 | 0.2 |
D20S102 | 2.39 | 0 | 0.10 | 0 | 1.49 | 0 | −0.11 | 0.2 | 3.88 | 0.2 |
D20S25 | 2.37 | 0 | 0.08 | 0 | 1.50 | 0 | 1.14 | 0 | 5.09 | 0 |
D20S86 | 0.90 | 0 | 1.49 | 0 | 1.50 | 0 | 0.30 | 0 | 4.19 | 0 |
stAFMa202yb9 | 0.07 | 0 | 0.20 | 0 | 0.53 | 0 | 0.80 | 0 | ||
GNAS | 0.34 | 0.1 | 1.44 | 0 | 0.40 | 0 | 0.26 | 0 | 2.44 | 0.1 |
D20S171 | 1.42 | 0.1 | 1.49 | 0 | 0.40 | 0 | 1.17 | 0 | 4.47 | 0.1 |
D20S64 | 1.50 | 0.1 | 0.52 | 0.1 | 1.50 | 0 | 0.08 | 0.2 | 3.60 | 0.4 |
D20S93 | 0.47 | 0.2 | 0.52 | 0.1 | 1.50 | 0 | 0.19 | 0.2 | 2.68 | 0.5 |
D20S173 | 1.25 | 0.1 | 0.24 | 0.2 | 1.20 | 0 | 1.10 | 0 | 3.79 | 0.3 |
Maximal lod scores (and the recombination fraction) for the different markers are shown for each kindred, as are the combined maximal lod scores; results identical to the maximal theoretical lod scores are in bold; the highest combined lod score is in bold italic.