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. 2004 Apr 26;165(2):203–211. doi: 10.1083/jcb.200309145

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Copyright © 2004, The Rockefeller University Press

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Figure 6. — Model for the vegetal RNA localization pathway. Vegetal RNA localization begins in the nucleus (gray) where hnRNP I (red) and Vg1RBP/vera (blue) bind to the RNA, forming a core nuclear RNP. Upon export to the cytoplasm, the RNP complex is remodeled such that hnRNP I and Vg1RBP/vera no longer directly interact. In the cytoplasm, Prrp (green) and XStau (yellow) associate with the RNP, creating the cytoplasmic localization RNP. In this model, a motor protein promotes transport to the vegetal cortex, where anchoring could occur via an interaction of Prrp with factors that promote actin dynamics.