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| ERAD-C substrates
|
ERAD-L substrates
|
|||||
|---|---|---|---|---|---|---|
| Ste6-166p | KSS | KWS | KHN | KWW | ||
| t 1/2 (min) | 8 | 10 | 4 | 35 | 35 | |
| Requires | CUE1 | yes | yes | yes | yes | yes |
| PEP4 | no | no | no | no | no | |
| SEC12 | no | no | no | yes | yes | |
| SEC18 | no | no | no | yes | yes | |
| DER1 | no | no | no | yes | yes | |
| HTM1/MNL1 | no | no | no | yes | yes | |
| HRD1/DER3 | no | no | no | yes | yes | |
| DOA10 | yes | yes | yes | no | no | |
