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. 2004 May 10;165(3):335–346. doi: 10.1083/jcb.200403061

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Copyright © 2004, The Rockefeller University Press

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Figure 3. — α- and β-synuclein are overexpressed in PS1 −/− neurons. (A) Increased levels of both α- and β-synuclein in PS1 −/− lysates were demonstrated with the synuclein antibodies Syn 202 and Syn 214. Other synaptic proteins including synapsin I and synaptophysin were increased only slightly in PS1 −/− neurons. NSE was used as a loading control. (B) ¹²⁵I-quantification of synuclein, synaptophysin, synapsin I, NFL, and tau levels relative to NSE. Error bars represent SD.