Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2004 Oct 11;167(1):43–50. doi: 10.1083/jcb.200406020

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2004, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — Binding of a PIPK peptide to talin head. (A) Diagram showing the domain structure of human PIPKIγ and the sequences of the PIPK peptides. Underlined residues indicate the talin binding region. (B–E) ITC traces showing the responses when either PIPK pep (B) or Mutant PIPK pep (D) was injected (arrow) into a chamber containing talin head (Tal H). Decreased magnitude of the response indicates talin saturation by PIPK pep. Dose–response curves show that PIPK pep (C), but not Mutant PIPK pep (E), binds to talin head. Data points were derived from B and D and were fit with a nonlinear least squares function (solid line).