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. 2004 Dec 20;167(6):1183–1194. doi: 10.1083/jcb.200403043

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Copyright © 2004, The Rockefeller University Press

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Figure 6. — Drugs affecting actin polymerization perturb actin cytoskeleton organization and decrease SF. Confocal analysis of Ecad doublets formed in suspension under control conditions (A), in the presence of Jasp (B) or LatB (C), and labeled for actin and E-cadherin. Merged images are shown in right panels. The images correspond to a medial transverse plane of the doublet. Dose-response curve of SF for 4-min Ecad doublets in medium containing Jasp (D) or LatB (E). (F) Mean SF for 30-s, 4- and 30-min doublets in the presence of 0.1 μM LatB (black bars), 0.1 μM Jasp (gray bars), or in control medium (white bars).