Table I. Directed melanosome movement in cells transfected with dynamatin and XKAP constructs.

Transfection	Anterograde movement	Retrograde movement	n
GFP	17.4 ± 8.2	8.7 ± 5.3	720
GFP–dynamitin	2.6 ± 4.6a	2.1 ± 3.8a	400
GFP–XKAP	2.0 ± 2.3a	1.7 ± 2.4a	300
GFP–N-XKAP	9 ± 5.7a	8 ± 7.5	200
GFP–C-XKAP	0.9 ± 3.0a	1.4 ± 2.3a	200

Melanosome movement was classified as any directional movement ≥2 μm with a rate ≥0.2 μm/s.

^aSignificant from GFP cells at 99.5% confidence level. Statistics were analyzed using Student's t test.