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. 2003 Jul 7;162(1):47–57. doi: 10.1083/jcb.200303019

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Copyright © 2003, The Rockefeller University Press

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Figure 7. — PF2 homologues. (A) Clustal W alignment of the deduced amino acid sequence of the Chlamydomonas reinhardtii (Cr) PF2 gene (AY309087–AY309089) with homologues identified by BLAST. The shaded areas represent identical or conservatively substituted amino acids in >50% of the sequences. The underlined region represents a putative microtubule-binding domain identified in the trypanosome and human orthologues (Hill et al., 2000). The abbreviation and GenBank/EMBL/DDBJ accession nos. for the sequences are as follows: Danio rerio (Dr), AI584969; Drosophila melanogaster (Dm), AE003427 and AA440118; Homo sapiens (Hs), AF050079; Mus musculus (Mm), U19859; Trypanosoma bruzi (Tb), AAB81499; and Trypanosoma cruzi (Tc), AQ44061. Gas11, growth arrest–specific 11; Gas8, growth arrest–specific 8. (B) Phylogenetic analysis of the Cr PF2 sequence and its homologues.