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. 2003 Jan 6;160(1):137–146. doi: 10.1083/jcb.200206049

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Copyright © 2003, The Rockefeller University Press

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Figure 2. — Haptotactic migration toward FN. (A) Wild-type fibroblasts (+/+) and two independently derived lines of PTPα^−/− fibroblasts (−/−) were analyzed for migration toward FN as described in Materials and methods. Each bar represents the average of four independent experiments, each experiment with three wells per cell type, ± S.D. The number of migrating wild-type cells was taken as 100%, and other values were calculated relative to this. (B) In other experiments, wild-type fibroblasts (+/+), line 2 PTPα^−/− fibroblasts (−/−), and line 2 PTPα^−/− fibroblasts infected with adenovirus expressing PTPα (α-wt) or catalytically inactive double mutant PTPα (α-dm) were analyzed for migration toward FN. Each bar represents the average of two independent experiments, each experiment with two wells per cell type, ± S.D.