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Number of facial and spinal motor neurons in the brain stem and lumbar (L1–L6) spinal cord, respectively, of 3.5-mo-old SMN2;Smn −/− type III SMA mice heterozygous for the A2G transgene and age-matched controls
| Type of motor neurons | Type III SMA | Normal | Reduction |
|---|---|---|---|
| Facial nucleus | 2,994 ± 94 (n = 4) | 3,695 ± 171 (n = 2) | −19% (P < 0.05) |
| Spinal motor neurons | 3,144 ± 201 (n = 4) | 4,421 ± 76 (n = 2) | −29% (P < 0.05) |
