Table I.
Ureteric bud branching in ret −/− , ret +/− , and ret +/+ urogenital explants with or without GDNF supplementation a
| No budding | <5 tips | >5 tips | |||||
|---|---|---|---|---|---|---|---|
| Control | GDNFb | Control | GDNF | Control | GDNF | Number of explants | |
| ret−/− | 7 | 7 | 9 | 4 | 4 | 9 | 20 |
| ret+/− | 0 | 0 | 8 | 4 | 12 | 16 | 20 |
| ret+/+ | 0 | 0 | 4 | 1 | 18 | 21 | 22 |
a
The results from the experiment shown in Fig. 1 E.
b
Urgenital blocks from each embryo were seperated by microdissection and cultured for 4 d. One side served as a control, the other one was cultured with 50 ng/ml of GDNF.