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. 2003 Apr 14;161(1):55–66. doi: 10.1083/jcb.200301026

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Copyright © 2003, The Rockefeller University Press

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Figure 4. — Sensory axon degeneration in KIF5A ^null /KIF5A^flox; Cre^synapsin mutant mice. (A) Ventral roots of 3-wk-old and 5.5-mo-old mutant mice. Note the lack of degeneration. Bar, 50 μm. (B) Dorsal roots of 3-wk-old and 5.5-mo-old mutant mice. Note the lack of degeneration in 3-wk sensory axons, but in the 5.5-mo-old mutant, there are large numbers of degenerating axons (arrowheads) and a striking decrease of large caliber axons. Bar, 20 μm.