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. 2003 Apr 28;161(2):267–280. doi: 10.1083/jcb.200208091

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Copyright © 2003, The Rockefeller University Press

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Figure 1. — ZM447439 inhibits Aurora A and Aurora B. (A) Chemical structure of ZM447439. (B) Table showing the IC₅₀ values (μM) of ZM447439 against a panel of protein kinases. (C) DNA content histograms of HeLa, A549, and HME cells treated with ZM447439 for the times indicated in hours. (D) Mitotic DLD-1 cells stained for phosphohistone H3 (green) and DNA (red).