Table I. Interactions between human PKP3 and fragments thereof with other desmosomal proteins as observed in the yeast two-hybrid system.
| Bait→Prey↓ | PKP3 | PKP3arm | PKP3head | PKP3ΔHR2 | PKP3headΔHR2 | p120ctn 3AC | Empty bait |
|---|---|---|---|---|---|---|---|
| Dsg1 | + | − | + | + | + | − | − |
| Dsg2 | + | − | − | + | − | − | − |
| Dsg3 | + | − | − | + | − | − | − |
| Dsc1a | + | − | − | + | − | − | − |
| Dsc1b | ± | − | − | ± | − | − | − |
| Dsc2a | + | − | − | + | − | − | − |
| Dsc2b | ± | − | − | ± | − | − | − |
| Dsc3a | + | + | + | + | + | − | − |
| Dsc3b | + | − | − | ± | − | − | − |
| Pg | + | − | − | + | − | ND | − |
| DPNTP | + | − | + | + | + | ND | − |
| DPNTPmut | + | − | + | − | − | ND | − |
| CK18 | + | − | + | + | + | ND | − |
| mEcad | − | − | − | − | − | + | − |
| Empty prey | − | − | − | − | − | − | − |
+, growth and blue staining of cotransformed yeast colonies on medium selective for interaction; −, no growth of cotransformed yeast colonies on medium selective for interaction; ±, severe reduction in both growth and blue staining of cotransformed yeast colonies on medium selective for interaction.