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. 2003 Jun 23;161(6):1093–1103. doi: 10.1083/jcb.200210169

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Copyright © 2003, The Rockefeller University Press

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Figure 7. — HSL accelerates PKA-stimulated, perilipin-mediated lipolysis in CHO cells. Basal activities are shown with solid lines, and activities stimulated with IBMX and forskolin are shown in dashed lines. Note that stimulated lipolysis in CHO cells expressing perilipin A alone (B) occurs only after a lag of 30 min, during which time forskolin stimulation has no effect on fatty acid efflux from the cells. Cells not infected with adenovirus perilipin were infected with Lac Z adenovirus. (A) Control cells expressing neither perilipin nor HSL; (B) CHO cells expressing HSL-GFP; (C) CHO cells expressing perilipin A; (D) CHO cells expressing HSL-GFP plus perilipin A.