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. 2003 Jun 23;161(6):1067–1079. doi: 10.1083/jcb.200303048

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Copyright © 2003, The Rockefeller University Press

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Figure 9. — A schematic model for the cell cycle- dependent control of the p97/p47 pathway. When a cell enters mitosis, p47 comes to the cytoplasm. However, p47 is phosphorylated by Cdc2 and its binding to Golgi membranes is inhibited, resulting in the Golgi fragmentation. At late mitosis, the p47 is dephosphorylated, and p97/p47 functions in membrane fusion for the Golgi reassembly. When a nuclear envelope is formed in a daughter cell, p47 is localized to the nucleus and the function of p97/p47 is suppressed. See Discussion for details.