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. 2002 Jul 8;158(1):115–125. doi: 10.1083/jcb.200112066

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Copyright © 2002, The Rockefeller University Press

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Figure 6. — Constitutive expression of DokR suppresses production of mature T cells but not mature B cells. (A) Flow cytometric analysis showing the percentage of GFP⁻ (top) and GFP⁺ (bottom) splenocytes expressing CD4 and CD8. The results shown are representative of data obtained from 7 to 13 mice per experimental group. (B) Flow cytometric analysis showing the expression of IgM and B220 on GFP⁻ (top) and GFP⁺ (bottom) splenocytes from reconstituted mice. The percentages of GFP⁻ and GFP⁺ B lymphocytes (IgM⁺B220⁺ cells) are indicated. Note that because of compensation for the high levels of fluorescence emitted by the GFP⁺ (B220⁺IgM⁺) B cells, the DN (B220⁻IgM⁻) population (bottom left) was partially obscured. Dot plots shown are representative of data pertaining to 7–13 mice per experimental group.