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. 2002 Oct 28;159(2):361–372. doi: 10.1083/jcb.200207050

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — PATJ is mainly found in the paranodal loops and only weakly in Schmidt-Lanterman incisures. Images of teased fibers from adult rat sciatic nerves, double labeled with an antiserum to PATJ (green) and a monoclonal antibody (red) to neurofilament, Caspr, or E-cadherin (Ecad). The merged images are shown on the right panel of each row. PATJ labeling surrounded that of Caspr, which marks the paranodal membrane of axons. PATJ antibody often labeled the incisures closest to the node (G and I, arrows), but was missing from all other E-cadherin–labeled incisures (I). Some weak staining of incisures was occasionally detected (J and L, arrows). Bar, 10 μm.