Table II. Effect of ionophore induced calcium increase on exocytosis of organelles in CHO cells.
Organelle | n = cells | Exocytic events (per min) observed in | Fold increase in rate of exocytosis induced by A23187 | |
---|---|---|---|---|
Untreated cells | 10 μM A23187- treated cells | |||
ER | n = 5 | 0 | 0 | – |
Golgi apparatus | n = 4 | 0 | 0 | – |
Post-Golgi vesicles | n = 6 | 6 ± 2 | 6 ± 2 | 0 |
Early endosomes | n = 5 | 0 | 0 | – |
Late endosomes | n = 6 | 0 | 0 | – |
Lysosomes | n = 8 | 1 ± 1 | 25 ± 14 | 25 |