Table III. The COOH-terminal fragment of p115 induces Golgi fragmentation and apoptosis independently in COS7 cells.
Transfected constructs | Cell morphology | Intact Golgi | Fragmented Golgi |
---|---|---|---|
% | % | ||
COOH-terminal fragment alone | Apoptotic | 7.0 | 93.0 |
COOH-terminal fragment + z-VAD-fmk | Normal | 23.5 | 76.5 |
COOH-terminal fragment + TEKD757Ala p115 | Apoptotic | 40.5 | 59.5 |
Results are the averages of duplicate samples from two separate experiments. In each case, 100–200 cells were counted by two independent observers.