Table 1.

Summary of parturition in COX-1, OT, and COX-1 KO/OT KO mice

Maternal genotype	Paternal genotype	PGF2α178	No.	Labor onset, d [range]	Avg. litter	Survival for 24 h, %
COX-1 KO	COX-1 KO	No	6	21.6 ± 0.2† [20.5–22.0]	7.5 ± 0.8	0
COX-1 KO	COX-1 KO	Yes	4	20.4 ± 0.1† [20.0–20.5]	6.3 ± 0.9	79
COX-1 KO	COX-1 Het/wt	No	7	22.0 + 0.5† [20.5–24]	8.0 ± 1.1	0
COX-1 KO/OT KO	COX-1 KO/OT KO	No	5	19.8 ± 0.5 [19–21.5]	8.6 ± 1.0	0
wt	wt	No	7	19.6 ± 0.1 [19.5–20.0]	8.9 ± 0.8	100

Labor onset and litter size are presented as mean ± SEM. Het, heterozygous. 

¹⁷⁸Bolus injection of 2.5 μg of prostaglandin F2β beginning at 19.5 d gestation. 

^†P < 0.001 vs. wt matings.