Figure 9.

Laminin-1 induces normal AChR clustering in src −/−;fyn −/− myotubes. C2, src −/−;fyn −/− and control wild-type cells were treated with 100 nM laminin-1 for 16 h and stained for AChRs with rhodamine-α-btx. Bar, 20 μm. Quantitation shows that laminin-1 induces similar clustering of AChRs in C2 and src −/−;fyn −/− cells. We analyzed two clones each of src −/−;fyn −/− and control wild-type cells, which all gave identical results to C2 (unpublished data). Data represent mean ± SEM of at least five experiments.