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. 2002 Oct 14;159(1):91–102. doi: 10.1083/jcb.200202114

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Copyright © 2002, The Rockefeller University Press

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Figure 11. — Role of LFA-1 and Mac-1 in chemotactic responses. (a) Migration of neutrophils to fMLP and IL-8 when treated with blocking antibodies to CD11a (LFA-1), CD11b (Mac-1), and CD18 (common subunit of CD11a and CD11b). (b) Migration of neutrophils treated with blocking antibodies to CD11a and CD11b in competing gradients of fMLP and IL-8. Results are shown as mean ± SEM (n = 12). *P < 0.05 compared with UT (isotype control).