Table II. CXCR1 and CXCR2 internalization in the presence of various stimuli.
IL-8 receptor
|
IL-8 alone
|
fMLP alone
|
IL-8 + fMLP
|
IL-8 + fMLP + SB203580
|
---|---|---|---|---|
% | ||||
CXCR1 | 78.3 ± 1.7 | 14.9 ± 13.8 | 82.8 ± 5.7 | 90.8 ± 1.5 |
CXCR2 | 72.0 ± 9.6 | 12.5 ± 4.8 | 74.3 ± 1.2 | 69.6 ± 1.7 |
Results are shown as the percentage of internalization ± SEM. n = 2 for IL-8 + fMLP and IL-8 + fMLP + SB203580. n = 3 for IL-8 and fMLP.