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. 2003 Dec 8;163(5):987–997. doi: 10.1083/jcb.200305083

Figure 7.

Figure 7.

Autophagy is greatly enhanced in GDNF-deprived sympathetic neurons. (A) Ultrastructure of a typical GDNF-maintained neuron with normal mitochondria (m), Golgi complex (G), and two dark autolysosomes (a) that are sparse in these neurons. (B) Typical GDNF-deprived neuron from sister dish showing largely increased number of autolysosomes, but normal mitochondria and Golgi complex. N, nucleus. (C). A detail from another GDNF-deprived neuron with double-membraned autophagosomes (ap) and single-membraned autolysosomes (al) containing swirled packages of undigested membranes. Bars, 1 μm.