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. 2003 Nov 10;163(3):463–468. doi: 10.1083/jcb.200305129

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Copyright © 2003, The Rockefeller University Press

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Figure 4. — Expression of the novel lipases in the mouse nervous system. DAGLα (a) and DAGβ (b) are expressed in neurofilament-positive axonal tracts (c) in the embryonic spinal cord (day 10). DAGLβ is expressed in the embryonic retinal ganglion fiber layer and optic nerve at day 14 (d). Note the lack of expression of DAGLα in the optic (e) and anterior commissures (f) in the adult. This contrasts with strong staining for the CB1 receptor in these tracts (g and h). DAGLα (i) and DAGLβ (j) expression in the adult cerebellum is restricted to the deep cerebellar nuclei and synaptic fields, including the Purkinje cell dendrites (k). Bar: (a–c) ∼130 μm; (d) ∼220 μm; (e–j) ∼500 μm; (k) ∼20 μm.