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. 2003 Nov 10;163(3):559–570. doi: 10.1083/jcb.200302157

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Copyright © 2003, The Rockefeller University Press

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Figure 6. — MyRIP controls the magnitude of secretory responses. SERT-transfected (black bars) or hGH-transfected PC12 cells (gray bars) were cotransfected with vectors encoding wild-type MyRIP (MyRIP 1–859), the Rab27A binding domain of MyRIP (MyRIP 1–134), a construct lacking the RBD (138–859), or MyRIP-ΔCter (1–665). Cells were incubated for 10 min in normal or high K⁺ saline. Release in normal saline medium was subtracted. Results are shown as percentage of the response of mock-transfected cells (mean ± SEM). The number of experiments performed is shown above the bars.