Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2003 Dec 22;163(6):1219–1230. doi: 10.1083/jcb.200306159

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2003, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 5. — PLA₂ is essential for nuclear shrinkage in hypoxic cells. (A) PC12 cells were incubated under normoxic (a) or hypoxic (b–h) conditions for 36 h. Before hypoxia, 50 μM zVAD-fmk (Z) and the indicated PLA₂ inhibitors were added to the culture medium. Nuclei were visualized under a fluorescence microscope after Hoechst 33342 staining. The average nuclear area is shown under the photographs. Arrows indicate apoptotic nuclei. Bars, 10 μm. (B) As described in Fig. 4 C, the percentage of cells with the indicated nuclear size was plotted.