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. 2002 May 13;157(4):565–570. doi: 10.1083/jcb.200202010

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Copyright © 2002, The Rockefeller University Press

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Figure 1. — The effects of MAG on neurons are dependent on p75 ^NTR . (A) Dissociated DRG neurons were incubated for 24 h with or without MAG–Fc and then immunostained with monoclonal antibody (TuJ1) recognizing the neuron-specific β–tubulin III protein. p75(+/+), wild type; p75(−/−), mice carrying a mutation in the p75^NTR gene. (B) Mean length of the longest neurite per neuron. Data are mean ± SEM. An asterisk indicates statistical significance (*p < 0.01, Student's t test). (C) Mean length of the longest neurite per neuron. Dissociated cerebellar neurons were incubated for 24 h with or without MAG–Fc.

Figure 1. — The effects of MAG on neurons are dependent on p75 ^NTR . (A) Dissociated DRG neurons were incubated for 24 h with or without MAG–Fc and then immunostained with monoclonal antibody (TuJ1) recognizing the neuron-specific β–tubulin III protein. p75(+/+), wild type; p75(−/−), mice carrying a mutation in the p75^NTR gene. (B) Mean length of the longest neurite per neuron. Data are mean ± SEM. An asterisk indicates statistical significance (*p < 0.01, Student's t test). (C) Mean length of the longest neurite per neuron. Dissociated cerebellar neurons were incubated for 24 h with or without MAG–Fc.