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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: J Biomol Screen. 2007 Oct;12(7):983–993. doi: 10.1177/1087057107307226

Table 5.

Effect of Compounds on Trypsin Activity

% Activity Remaining

Compound IC50a 200 μM
DMSO 100.0 ± 8.7 100.0 ± 8.5
TLCK ND 41.5 ± 0.4
1 94.2 ± 2.4 94.5 ± 1.3
2 118.5 ± 2.2 123.6 ± 8.0
3 73.5 ± 3.3 3.0 ± 1.4
4 89.6 ± 3.1 24.9 ± 0.9
5 76.9 ± 2.3 40.8 ± 4.3
6 103.4 ± 1.0 56.5 ± 1.6
7 103.3 ± 1.5 46.8 ± 2.5
8 99.3 ± 2.1 14.4 ± 2.2
9 101.1 ± 3.9 38.3 ± 0.9

ND, not determined.

a

As reported in Table 3 for Sc Rce1p. Values are derived from 4 independent measurements.