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. Author manuscript; available in PMC: 2009 Jan 4.
Published in final edited form as: J Mol Biol. 2007 Oct 16;375(1):202–216. doi: 10.1016/j.jmb.2007.10.017

Figure 1. Nucleotide and translated amino acid sequences for variable regions.

Figure 1

(a) The light chain variable region of 13F6-1-2 compared with the BALB/c Vλx germline (GenBank accession number M34597), and the Vλx-light chains F28C4 (GenBank accession number X76752) and MW1 (GenBank accession number M34598). 13F6-1-2 contains two mutations from the Vλx germline: a Ser to Arg mutation at residue 27 in CDR L1 and a Lys to Arg mutation in framework residue 45. (b) The heavy chain variable region of 13F6-1-2 compared with the germline VH283 and F28C4. The amino acids are labeled according to the Kabat numbering scheme and hypervariable loops are highlighted in colour.

HHS Vulnerability Disclosure