Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mouse ES cells containing defective Msh2 genes fail to efficiently execute cell death (apoptosis) in response to low-level radiation treatment. Apoptosis induction was assessed by using flow cytometry to monitor the appearance of cells containing fragmented DNA (see Materials and Methods) for wt ES cells (Msh2+/+) and for ES cells carrying disrupted Msh2 genes (Msh2+/− and Msh2−/−) after exposure to low-level ionizing radiation for 24 h. Mean values ± SEM are displayed.
