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. 2002 Feb 18;156(4):751–760. doi: 10.1083/jcb.200105147

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — Western blot using an antibody against GATA-2 transcription factor, a marker for skeletal muscle hypertrophy. In both gracilis anterior and posterior the WT muscle contained the least amount of GATA-2 protein, followed by an equal level in IGF and WT-EX muscles. IGF-EX muscles had the highest expression of GATA-2 protein, indicating that exercise and the mIGF-1 transgene synergize to increase muscle hypertrophy.