Figure 1.

Influence of unc-104 mutations on CSP distribution in larval axons. CSP, a vesicle associated protein, was immunolocalized in wild-type (A, D, and G), unc-104^O1.2/unc-104^P350 mutant (B, E, and H), and Khc⁶/Khc²⁷ mutant (C, F, and I) third instars. (A–C) Segmental nerves. (D–F) Motor axon terminals on muscle 6/7. (G–I) Motor axon terminals on muscles 12/13. Note that unc-104 mutations did not cause CSP accumulation in the sort of focal axonal swellings that are caused by Khc mutations (short arrows in C). However, unc-104 mutations did seem to cause a reduction in terminal size that was particularly noticeable for the terminals on muscles 12/13 (G–I). Bar, 10 μm.