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. 1999 Oct 18;147(2):295–306. doi: 10.1083/jcb.147.2.295

Figure 2.

Figure 2

Cells forced into premature mitosis by cyclin A often fail to condense fully their chromosomes. HeLa cells were synchronized in G2 phase and injected with 2–4 μM cyclin A/CDK2 as in Fig. 1 A. Representative DIC images are shown of a cell that does (A) and a cell that does not (B) fully condense its chromosomes at metaphase. The cell that does not condense its chromosomes divides but the daughter cells fuse.