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. 2000 Mar 20;148(6):1295–1304. doi: 10.1083/jcb.148.6.1295

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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A, High magnification of Timm-stained horizontal sections of the injected side of DG of wild-type, tPA^−/−, and plg^−/− mice near the tip of the injected DG. The arrows point to the newly formed mossy fiber sprouts, demonstrating that they accumulate and extend along the border of the granule cell and molecular layers. B, PSA-NCAM immunohistochemistry on horizontal sections of the injected side of DG of wild-type, tPA^−/−, and plg^−/− mice near the tip of the injected DG. The arrows point to the extending neurites through the granule cell layer (GCL), the arrowheads point to the accumulated PSA-NCAM expression on the border between GCL and molecular layer (mol).