Table 1.
First Author (ref) | Year | Type | Ca type | Out-come | Size (cm) | LN (+ of total) | EM | Synp | Chr | E-cad | any CK | Ki-67 |
Nagoaka [13] | 1996 | Cmp | NR | DOD | 8 | NR | NR | NR | A-; NE+ | NR | NR | NR |
Fujiyoshi [4] | 2004 | Cmp | sign | NED @ 9 y | NR | 0 of 13 | NR | A-; NE- | A+; NE+ | A- NE+ | A-; NE- | NR |
Fujiyoshi [4] | 2004 | Cmp | sign | NED @ 8 y | 10.5 | 0 of 9 | NR | A-; NE- | A+; NE+ | A- NE+ | A-; NE- | NR |
Adhikari [6] | 2002 | Cmp | int | NED @ 1 y | 6 | NR | NR | A+f; NE+ | A+f; NE+ | A+f; NE+ | A+; NE- | NR |
Caruso [7] | 1989 | Cmp | int | NR | 1.5 | NR | NR | NR | A+; NE+ | NR | NR | NR |
Yang [10] | 1991 | Cmp/Amp | int | NED @ 6 mo | 3 | 18 of 19 | NE/M same | NR | + | NR | NR | NR |
Ulich [14] | 1988 | Cmp | int | NR | 3.6 | NR | NR | NR | A+f; NE+ | NR | NR | NR |
Wheeler [15] | 1983 | Cmp | int | DOD @ 3 mo | 5 | NR | NR | NR | NR | NR | NR | NR |
Ali [16] | 1984 | Cmp | sign | DOD | 22 | 0 of 5 | NE/M same | NR | NR | NR | NR | NR |
Brouland [17] | 2001 | Cmp/Amp | sign | NED @ 6 mo | NR | NR | NE/M same | NR | + | NR | NR | NR |
Jain [18] | 2005 | Cmp | int | LTFU | 1.5 | NR | NR | A+f; NE+ | A+f; NE+ | NR | A+; NE- | NR |
Jain [18] | 2005 | Cmp | int | NED @ 2 y | 3.3 | NR | NR | A+f; NE+ | A+f; NE+ | NR | A-; NE- | NR |
Jain [18] | 2005 | Cmp | int | DUC @ 4 mo | NR | NR | NR | A+f; NE+ | A+f; NE+ | NR | NR | NR |
Klappenbach [5] | 1985 | Cmp | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
Pasquinelli [19] | 1993 | Cmp/Amp | NR | DOD | 3 | NR | NE/M same | + | + | NR | NR | NR |
Present case | 2007 | Cmp | sign | NED @ 6 mo | 3.5 | 3 of 12 | NE/M diff | A+; NE+ | A+; NE+ | A+; NE- | A+; NE- | A+; NE- |
Abbreviations: +, positive immunolabeling; -, negative; A, adenocarcinoma; Amp, amphicrine; Ca, carcinoma; Chr, chromogranin A; CK, cytokeratin; Cmp, composite; DOD, dead of disease; DUC, dead of unrelated causes; E-cad, e-cadherin; EM, electron microscopy; f, focal; diff = different. intest = intestinal; LN, lymph nodes; LTFU, lost to follow up; M, mucous; NE, neuroendocrine; NED, no evidence of disease; NR, not reported; sign = signet; Synp, synaptophysin;