Table 1.
Sensitivities and specificities of WB rapid and panLF rapid tests evaluated at five institutions.
| WB rapid | panLF rapid | |||||||||
| Wb | Bm/Bt | *Other infec-tions | Nor-mals | Sens & Spec | Wb | Bm/Bt | *Other infections | Normals | Sens & Spec | |
| UI | 43 (43) | - | 0 (13) | - | 100% sens 100% spec |
24 (24) | 35 (38) | - | - |
Overall sens: 95% Wb: 100% sens Bm: 92% sens |
| UM | 30 (30) | - | 0 (58) | 0 (10) | 100% sens 100% spec |
30 (30) | 29 (29) | 0 (60) | 0 (10) |
100% sens (Bm & Wb) 100% spec |
| AMU | 102 (104) | - | - | 0 (48) | 98% sens 100% spec |
99 (104) | - | - | 0 (48) |
95% sens (Wb) 100% spec |
| USM | 47 (50) | - | 1 (65) | 0 (50) | 94% sens 99% spec |
47 (50) | 109 (111) | 1 (65) | 0 (50) |
Overall sens: 97% Wb: 94% sens Bm: 98% sens 99% spec |
| ILS | 17 (18) | - | - | - | 94% sens | 17 (18) | - | - | - | 94% sens (Wb) |
Note: Numbers indicate number of samples that were positive, and numbers in parenthesis were the number of samples tested.
UI : University of Indonesia, Indonesia
UM : University of Malaya, Malaysia
AMU : Aichii Medical University, Japan
USM : Universiti Sains Malaysia, Malaysia
ILS : Institute of Life Sciences, India
sens : sensitivity; spec : specificity
Wb: Wuchereria bancrofti ; Bm: Brugia malayi ; Bt: Brugia timori
Filarial samples tested in Indonesia, Malaysia and India came from mf+ individuals; while those tested in Japan also came from individuals who are mf-, CFA+ (>512 units).
*Other infections: ascariasis, trichuriasis, hookworm, strongyloidiasis, toxocariasis, toxoplasmosis, typhoid, cysticercosis, schistosomiasis, malaria, dengue, amoebiasis
WB rapid: sensitivity : 97.6% (239/245); specificity : 99.6% (243/244)
panLF rapid: overall sensitivity : 96.5% (390/404); sensitivity for Wb detection: 96.0% (217/226); sensitivity for Bm/Bt detection: 97.2% (173/178); specificity: 99.6% (232/233)