Table 3.
Summary of significant affected genes (27) in the trxB1 over-expression strain, NZ7602, when compared to the wild type (pvalue < 0.01 & FC ≥ 1.5). Predicted gene names, function, fold change induction as well as main functional classes of the significant affected transcripts are displayed in columns. Main functional classes presented in bold are those classes found overrepresented in this study when compared to the total genome of L. plantarum.
| Locus | FC2 trx/wt | Gene | Product | Main Functional Class (%)1 |
| lp_0254 | 1,5 | cysE | serine O-acetyltransferase | Amino acid biosynthesis (4%) |
| lp_3421 | 1,6 | extracellular protein, gamma-D-glutamate-meso-diaminopimelate muropeptidase (putative) | Cell envelope (7%) | |
| lp_2716 | 1,6 | ica3 | glycosyltransferase (putative) | |
| lp_0728 | 0,6 | groEL | GroEL chaperonin | Cellular processes (7%) |
| lp_2544 | 1,6 | npr2 | NADH peroxidase | |
| lp_3020 | 1,6 | tag2 | DNA-3-methyladenine glycosylase I | DNA metabolism (4%) |
| lp_0789 | 1,7 | gapB | glyceraldehyde 3-phosphate dehydrogenase | Energy metabolism (4%) |
| lp_1237 | 1,5 | unknown | Hypothetical proteins (19%) | |
| lp_1081 | 1,6 | unknown | ||
| lp_1611 | 2,1 | unknown | ||
| lp_1708 | 2,3 | unknown | ||
| lp_1880 | 3,9 | unknown | ||
| lp_1023 | 1,8 | type 4 prepilin-like proteins leader peptide processing enzyme (putative) | Protein fate (4%) | |
| lp_2119 | 1,7 | tuf | elongation factor Tu | Protein synthesis(4%) |
| lp_2721 | 1,5 | purN | phosphoribosylglycinamide formyltransferase | Purines, pyrimidines, nucleosides and nucleotides (15%) |
| lp_2722 | 1,6 | purM | phosphoribosylformylglycinamidine cyclo-ligase | |
| lp_2729 | 1,7 | purE | phosphoribosylaminoimidazole carboxylase, catalytic subunit | |
| lp_0761 | 23,5 | trxB1 | thioredoxin reductase (NADPH) | |
| lp_1230 | 1,6 | transcription regulator | Regulatory function (4%) | |
| lp_3278 | 1,8 | amino acid transport protein | Transport and binding proteins (11%) | |
| lp_1087 | 1,8 | cation transport protein | ||
| lp_2992 | 2,6 | mntH2 | manganese transport protein | |
| antilp_3469 | 1,6 | |||
| lp_RNA02 | 2,6 | plasmids (15%) | ||
| lp_p2_01 | 3,1 | |||
| lp_p2_02 | 3,2 | |||
| lp_p3_05 | 1,5 |
1values given in parenthesis correspond to the percentage of the total amount of genes (27) that belong to each depicted functional class.
2FC is fold change or 2M